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Can Headache Happen After Taking Ella?

Headaches can occur after taking Ella emergency contraception. Learn how common they are, how to ease discomfort, and when to seek medical care promptly.

By Caleb Bennett Reviewed by Dr. Irene Medical review dateDec 31, 2025 6 min read

Yes. A headache can happen after taking Ella (ulipristal acetate), an emergency contraceptive pill. Headache is one of its commonly reported side effects; the U.S. National Library of Medicine's DailyMed label reports it in about 18% of participants in clinical studies. A headache alone does not show whether the pill worked or whether pregnancy occurred. Rest, drink water, and seek advice if pain is severe or persistent.

How common is a headache after taking Ella?

Headache is a recognized side effect of Ella, which contains ulipristal acetate and is used for emergency contraception after unprotected sex or contraceptive failure. In clinical trials, headache was reported by approximately 18% of participants overall. This makes it one of the more commonly reported side effects of the medication, although not everyone who takes Ella will experience it.

What other side effects may occur alongside a headache?

A headache may occur on its own or alongside other side effects. MedlinePlus, a service of the U.S. National Library of Medicine, lists several other possible effects of ulipristal acetate, including:

  • Nausea or an unsettled stomach.
  • Tiredness or fatigue.
  • Dizziness.
  • Painful menstrual periods.
  • Spotting or bleeding between menstrual periods.

These effects do not necessarily occur together. Their presence or absence also cannot establish whether Ella has prevented pregnancy.

How long can a headache last after taking Ella?

The prescribing information identifies headache as a side effect but does not specify exactly when an Ella-related headache should begin or how long it should last. Headaches have different durations, and not every headache that occurs after taking a medicine is necessarily caused by that medicine.

If your headache is not improving, continues to return, becomes worse, or interferes with sleep or everyday activities, contact a healthcare professional. They can consider when the headache started, whether you have experienced similar headaches before, your other symptoms, and any medicines you take.

What can you do to relieve a headache after Ella?

If the headache is manageable and you have no concerning symptoms, a few simple measures may help you feel more comfortable. The NHS headache guidance recommends practical steps such as:

  • Drinking enough water throughout the day.
  • Eating regular meals rather than skipping food.
  • Getting adequate rest and taking time to relax.
  • Limiting prolonged screen use if it makes the pain worse.
  • Avoiding alcohol while you are experiencing the headache.

If you need a pain reliever, ask a pharmacist or healthcare professional which option is suitable for you, particularly if you might be pregnant, have a medical condition, or take other medicines. Follow the medicine's package directions and do not take more than the recommended dose.

Does a headache mean Ella has failed or that you are pregnant?

No. A headache by itself cannot tell you whether Ella has worked or whether pregnancy has occurred. Headache is a known side effect, and its presence does not establish that emergency contraception has failed.

Ella can also change the timing of your next menstrual period. The official prescribing information published on DailyMed advises ruling out pregnancy if your expected period is delayed by more than one week. A pregnancy test and appropriate medical advice can help clarify the situation.

When should you seek medical attention for a headache after Ella?

Do not assume that every headache after taking Ella is a medication side effect. Seek medical advice if the pain is persistent, worsening, unusual for you, or disruptive to normal activities. A healthcare professional can assess the headache in the context of your medical history and any other symptoms.

Seek emergency medical attention if the headache starts suddenly and is extremely painful, or if it occurs with symptoms such as weakness, numbness, trouble speaking, difficulty walking, confusion, fainting, seizures, vision loss, fever, or a stiff neck. Mayo Clinic's guidance on headaches identifies these as warning signs that may require urgent assessment.

You should also seek immediate medical help if you develop a serious allergic reaction, such as swelling of the face, tongue, or throat, or widespread hives after taking Ella. Do not wait for these symptoms to resolve on their own.

In summary, headache is a recognized side effect of Ella and does not automatically indicate a problem with the medication or a pregnancy. Simple self-care may help, but persistent or worsening pain deserves medical attention, and sudden severe headaches or headaches with neurological symptoms require emergency assessment.

Frequently Asked Questions

Common questions about headaches after taking Ella and what to do next.

Can a headache start soon after taking Ella?

Yes, a headache can occur after taking Ella. However, official prescribing information does not specify an exact time when the headache must begin. A headache occurring afterward does not, by itself, prove that the medicine caused it.

How long should I wait for a headache after Ella to go away?

There is no fixed duration for an Ella-related headache. Drink water, eat regular meals, and rest if these measures help. Contact a healthcare professional if the headache persists, gets worse, keeps returning, or affects daily activities. Seek emergency care for a sudden, extremely painful headache or concerning accompanying symptoms.

Does having a headache after Ella mean I am pregnant?

No. A headache cannot confirm or rule out pregnancy. Ella can affect the timing of your next period. If your expected period is more than one week late, the official prescribing information recommends ruling out pregnancy with appropriate testing or medical evaluation.

When is a headache after Ella an emergency?

Seek emergency medical attention for a sudden, extremely painful headache or one accompanied by weakness, numbness, difficulty speaking, confusion, vision loss, seizures, fever, or a stiff neck. Swelling of the face, tongue, or throat after taking Ella also needs immediate medical attention.

Citations

  1. DailyMed — ELLA (ulipristal acetate) prescribing information
  2. MedlinePlus — Ulipristal Drug Information
  3. NHS — Headaches
  4. Mayo Clinic — Headache: Causes and When to Seek Medical Care
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