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Can Rheumatoid Arthritis Improve in Pregnancy?

Rheumatoid arthritis may improve during pregnancy, but symptoms can persist or worsen. Learn what affects disease activity, treatment safety, and postpartum flares.

By Caleb Bennett Reviewed by Dr. Irene Medical review dateOct 4, 2025 9 min read

Yes, rheumatoid arthritis can improve during pregnancy, and some women experience less joint pain, swelling, and morning stiffness. However, improvement is not guaranteed, and symptoms may continue or worsen in some women. Pregnancy-related changes in the immune system may help explain this improvement. After childbirth, rheumatoid arthritis symptoms often return or flare, so planning treatment with a rheumatologist and obstetrician is important.

Why can rheumatoid arthritis improve during pregnancy?

Rheumatoid arthritis (RA) is an autoimmune disease in which the immune system mistakenly attacks the lining of the joints, causing inflammation. Common effects include pain, swelling, stiffness, and difficulty moving affected joints.

During pregnancy, the immune system changes to support the developing baby. These changes may also reduce rheumatoid arthritis activity in some women. Researchers have observed that pregnancy can bring relief from joint symptoms, although the exact reasons for this improvement are not fully understood.

According to the Arthritis Foundation, research has found that rheumatoid arthritis activity improves in many women during pregnancy. However, improvement does not mean the disease has disappeared or that treatment and medical monitoring are no longer needed.

How often does rheumatoid arthritis improve during pregnancy?

Many women experience some relief, but the degree of improvement varies. Some notice less joint swelling and stiffness, while others continue to have symptoms throughout pregnancy. A smaller proportion may experience worsening disease activity.

A review of research summarized by the Arthritis Foundation found improvement in rheumatoid arthritis activity in approximately 60% of patients during pregnancy. These findings describe a group of patients and cannot predict how a particular pregnancy will affect an individual.

More recent patient information from MotherToBaby, updated in July 2026, reports that around half of women with rheumatoid arthritis experience symptom relief during pregnancy. The difference between reported estimates reflects differences in the studies and populations considered.

What rheumatoid arthritis symptoms may improve?

When rheumatoid arthritis becomes less active during pregnancy, women may notice changes in several aspects of daily life. Examples include:

  • Less pain in the hands, wrists, feet, or other affected joints.
  • Reduced joint swelling and tenderness.
  • Less stiffness after waking up or sitting for a long time.
  • Improved ability to perform everyday activities, such as dressing, preparing meals, or walking.
  • Less difficulty using the hands for gripping or other routine tasks.

These improvements are not universal. Pregnancy can also cause fatigue, back discomfort, and other physical changes that may affect daily activities independently of rheumatoid arthritis. A healthcare professional can help distinguish pregnancy-related discomfort from changes in joint inflammation when symptoms are difficult to interpret.

Does rheumatoid arthritis improve throughout all three trimesters?

There is no single pattern that applies to every pregnancy. Some women notice improvement during the early months, while others experience relief later or have symptoms that fluctuate throughout pregnancy. Some do not experience meaningful improvement at any stage.

For this reason, rheumatoid arthritis should be monitored throughout pregnancy rather than assuming that symptoms will settle after a particular week. Changes in joint pain, swelling, stiffness, and physical function can help the rheumatology team assess how well the disease is controlled.

Can rheumatoid arthritis get worse during pregnancy?

Yes. Although improvement is common, pregnancy does not reliably suppress rheumatoid arthritis in every woman. Some women continue to have active inflammation, and others experience increased symptoms.

Active rheumatoid arthritis deserves attention because poorly controlled disease is associated with a greater chance of certain pregnancy complications, including preterm delivery and having a baby who is smaller than expected for the stage of pregnancy. The MotherToBaby rheumatoid arthritis fact sheet discusses these associations and emphasizes the importance of controlling the disease during pregnancy.

Persistent or worsening joint swelling, increasing pain, or difficulty with everyday activities should be discussed with the treating clinician. The goal is to maintain good disease control while choosing treatments appropriate for pregnancy.

What happens to rheumatoid arthritis after childbirth?

Rheumatoid arthritis may become active again after delivery, even when symptoms improved considerably during pregnancy. This return of inflammation is often called a postpartum flare. It can occur during the first weeks or months after childbirth and may bring back joint pain, swelling, and morning stiffness.

MotherToBaby reports that around half of women with rheumatoid arthritis may experience a flare during the first several months after pregnancy. The timing and intensity vary, so improvement during pregnancy should not be taken as a sign that symptoms will remain controlled after delivery.

Postpartum planning matters because joint symptoms and fatigue can make caring for a newborn more physically demanding. Arranging practical help with lifting, feeding, bathing, and other daily tasks may be useful if symptoms return.

Can rheumatoid arthritis medication be continued during pregnancy?

Some rheumatoid arthritis medicines can be used during pregnancy, while others need to be changed or stopped before conception. The right approach depends on the specific medicine, the activity of the disease, and the potential risks of both medication exposure and untreated inflammation.

The Arthritis Foundation's guidance on arthritis medications during pregnancy explains that medication safety differs between drug classes. Methotrexate, for example, is generally avoided during pregnancy because of its potential to harm fetal development. Other disease-modifying medicines may be suitable under medical supervision.

Do not stop, reduce, or replace a prescribed medicine on your own because you are pregnant or your symptoms have improved. Suddenly stopping effective treatment can allow inflammation to return. If pregnancy is planned, a rheumatologist can review the current treatment and make any necessary changes in advance. If pregnancy occurs unexpectedly, contact the prescribing clinician promptly for individualized advice.

How can you prepare for pregnancy with rheumatoid arthritis?

Planning ahead helps balance control of rheumatoid arthritis with the health of the developing baby. Ideally, discuss pregnancy with both a rheumatologist and an obstetrician before trying to conceive. This gives the care team time to review disease activity, current medicines, and the monitoring needed during pregnancy.

When possible, healthcare professionals aim to achieve stable disease control before conception and maintain it throughout pregnancy. The European Alliance of Associations for Rheumatology (EULAR), in its updated recommendations on antirheumatic medicines during reproduction, pregnancy, and breastfeeding, emphasizes balancing the potential risks of medication against the risks of untreated disease.

During pregnancy, useful steps include attending scheduled appointments, reporting changes in symptoms, and checking before taking new prescription medicines, over-the-counter pain relievers, or supplements. After delivery, arrange follow-up care to review symptoms and decide whether treatment needs to be adjusted, particularly if breastfeeding is planned.

Does improvement during pregnancy mean rheumatoid arthritis is cured?

No. Symptom relief during pregnancy does not mean rheumatoid arthritis has been cured. It may reflect a temporary change in disease activity associated with pregnancy. The underlying condition can remain present even when joint pain and stiffness become less noticeable.

For this reason, treatment decisions should be based on the overall pattern of disease activity and the safety of available medicines, not simply on whether symptoms have improved. Continued monitoring helps identify a return of inflammation and supports an appropriate treatment plan after childbirth.

Frequently Asked Questions

Common questions about rheumatoid arthritis, pregnancy, and changes in symptoms before and after delivery.

Can rheumatoid arthritis go into remission during pregnancy?

Some women experience a substantial reduction in rheumatoid arthritis activity during pregnancy, sometimes reaching remission. However, this does not happen to everyone, and symptom improvement alone does not establish that the disease is in remission. Medical monitoring remains important.

When does rheumatoid arthritis usually improve during pregnancy?

There is no fixed time when improvement begins. Some women notice relief during pregnancy, while others have ongoing or fluctuating symptoms. The pattern varies between individuals, so regular assessment is more useful than expecting improvement during a particular trimester.

Why does rheumatoid arthritis flare after giving birth?

Changes in the immune system and hormones around pregnancy and childbirth may contribute to a return of rheumatoid arthritis activity. The exact reasons are not fully understood. A postpartum treatment plan can help address returning symptoms while taking breastfeeding considerations into account.

Should I stop rheumatoid arthritis medication if my symptoms improve during pregnancy?

No. Do not stop or change prescribed treatment without discussing it with your healthcare team. Some medicines are compatible with pregnancy, while others require adjustment. Keeping inflammation controlled is important for your health and may also support a healthier pregnancy.

Can women with rheumatoid arthritis have a healthy pregnancy?

Yes. Many women with rheumatoid arthritis have healthy pregnancies and babies. Planning pregnancy when the disease is well controlled, reviewing medication safety, and receiving coordinated care from a rheumatologist and obstetrician can help reduce avoidable risks.

Citations

  1. Arthritis Foundation: Rheumatoid Arthritis and Pregnancy
  2. MotherToBaby: Rheumatoid Arthritis
  3. Arthritis Foundation: Arthritis Medications During Pregnancy
  4. European Alliance of Associations for Rheumatology: Recommendations for Use of Antirheumatic Drugs in Reproduction, Pregnancy, and Lactation
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