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Infection After Fibroid Surgery: Signs

Learn the signs of infection after fibroid surgery, including fever, worsening pain, unusual discharge, and wound changes, and when to seek medical care.

By Caleb Bennett Reviewed by Dr. Irene Medical review dateNov 7, 2025 9 min read

Signs of infection after fibroid surgery may include fever, chills, increasing abdominal pain, redness or swelling around an incision, and pus or foul-smelling discharge. Some people also experience unusual vaginal discharge, heavy bleeding, or a general feeling of being unwell. These symptoms need medical attention, especially when they worsen or appear after initial improvement. Contact your surgical team promptly if you notice possible signs of infection.

What are the common signs of infection after fibroid surgery?

Fibroid surgery, also called myomectomy when fibroids are removed while preserving the uterus, can be performed through an abdominal incision, small laparoscopic incisions, or the vagina using a hysteroscope. The possible signs of infection depend partly on the surgical approach and the area affected.

After surgery, some soreness and mild discomfort are expected during healing. However, symptoms that become more noticeable, return after improving, or occur alongside a fever deserve attention. The following signs may be associated with an infection and should be assessed in the context of your recovery.

  • Fever or chills: A raised temperature, shivering, or feeling unusually cold may occur with an infection. A fever of 38°C (100.4°F) or higher warrants urgent medical assessment after surgery.
  • Increasing abdominal or pelvic pain: Pain that becomes worse instead of gradually improving may indicate a complication, including infection.
  • Redness, warmth, or swelling around an incision: The skin around a surgical wound may become increasingly red, tender, warm, or swollen.
  • Pus or unusual wound drainage: Thick yellow or green fluid, cloudy discharge, or fluid with an unpleasant smell may indicate a wound infection.
  • Unusual vaginal discharge: Discharge that smells unpleasant or changes significantly in appearance may require assessment, particularly when accompanied by fever or pelvic pain.
  • Feeling generally unwell: Weakness, chills, or a marked decline in how you feel may occur alongside other signs of infection.

According to University College London Hospitals NHS Foundation Trust, increasing wound redness or pain, pus-like discharge, and fever are signs that should prompt contact with the healthcare team after gynaecological surgery.

How can infection appear at different surgical sites?

Infection does not always develop in the same place. The type of fibroid procedure helps determine which symptoms are most relevant, and an infection may affect the incision or an internal area.

Infection around an abdominal incision

After open abdominal myomectomy, an infection may develop in the skin or tissues around the surgical cut. Following laparoscopic or robotic surgery, similar changes can appear around one or more small incisions.

Watch for redness that spreads, increasing tenderness, warmth, swelling, wound edges that separate, or drainage that becomes thick or foul-smelling. A small amount of early wound drainage may occur during healing, but increasing or abnormal drainage should be reported.

MedlinePlus describes surgical wound infection as potentially causing redness, pain, warmth, pus drainage, fever, and a general feeling of illness. These signs are reasons to contact your healthcare professional rather than attempting to assess the wound yourself.

Possible infection inside the pelvis or uterus

An infection affecting deeper tissues may not cause obvious changes around the skin incision. Possible warning signs include fever, worsening lower abdominal or pelvic pain, unusual vaginal discharge, or unexpected heavy bleeding.

These symptoms can have causes other than infection, so their presence alone does not establish what is happening. However, new or worsening symptoms after fibroid surgery should be discussed promptly with your surgeon, particularly when several occur together.

Infection after hysteroscopic fibroid removal

Hysteroscopic myomectomy removes fibroids through the vagina and cervix using a thin instrument, without an abdominal incision. Because there is no abdominal skin wound, infection-related changes may be more noticeable through fever, pelvic discomfort, or abnormal vaginal discharge.

Some vaginal spotting or mild cramping can occur after gynaecological procedures. Heavy bleeding, worsening pain, fever, or discharge with an unpleasant smell should not be dismissed as routine recovery symptoms.

When do signs of infection usually appear?

An infection may become apparent during the first several days of recovery or later. Surgical wound infections often develop within the first 30 days after an operation, according to MedlinePlus. This is a general timeframe for surgical wound infections, not a guarantee about when complications after fibroid surgery will occur.

Pay attention to changes throughout recovery rather than relying on a specific day. For example, pain that steadily improves is different from pain that begins worsening after several days. Similarly, a new fever or unusual discharge after you have started feeling better should be reported to your healthcare team.

An infection can also occur without every typical sign being present. The absence of fever or visible wound changes does not completely exclude an internal problem.

How is infection different from normal recovery?

Recovery after fibroid surgery can involve temporary discomfort, tiredness, mild cramping, and some vaginal spotting, depending on the procedure. These symptoms should generally follow the recovery pattern described by your surgical team.

Changes that are more concerning include pain that steadily increases, a new or persistent fever, worsening wound redness, pus, or discharge with an unpleasant smell. Heavy vaginal bleeding also needs prompt medical assessment, even though it does not necessarily indicate infection.

The distinction is not always obvious. According to the American College of Obstetricians and Gynecologists (ACOG), fever, severe or worsening pain, heavy vaginal bleeding, and redness, swelling, or discharge from an incision are warning signs after laparoscopy that require contact with an obstetrician-gynaecologist.

When should you seek medical attention?

Contact your surgeon or gynaecologist promptly if you develop possible signs of infection after fibroid surgery. Do not wait for several symptoms to appear together or for the next scheduled follow-up appointment if your condition is getting worse.

Seek urgent medical assessment if you experience:

  • A temperature of 38°C (100.4°F) or higher.
  • Severe or worsening abdominal or pelvic pain.
  • Heavy vaginal bleeding, particularly bright red bleeding or large blood clots.
  • Pus-like discharge or a surgical wound that opens.
  • Persistent vomiting that prevents you from drinking fluids.

Seek emergency care if you develop severe weakness with collapse, fainting, confusion, difficulty breathing, or other signs of serious illness. Do not delay emergency care while waiting to contact your surgeon.

These recommendations are consistent with the postoperative warning signs described by University College London Hospitals NHS Foundation Trust, which advises urgent assessment for symptoms including fever, severe or worsening pain, and heavy vaginal bleeding.

What should you do if you suspect an infection?

Contact the team responsible for your operation and describe your symptoms, when they began, and whether they are improving or worsening. Mention any measured temperature, changes in vaginal discharge, wound drainage, or changes in bleeding. These details can help the clinician determine how quickly you need to be examined.

Keep the incision clean and follow the wound-care instructions provided at discharge. Wash your hands before touching the wound or changing its dressing, and avoid applying creams, antiseptics, or other products unless your healthcare professional recommends them.

Do not take leftover antibiotics or start treatment without medical guidance. If an infection is suspected, a clinician may examine the wound, assess your abdomen, review your symptoms, and arrange blood tests, imaging, or other investigations when appropriate. Treatment depends on the location and nature of the problem.

Frequently Asked Questions

Frequently Asked Questions

Answers to common questions about recognising infection after fibroid surgery.

Can you have an infection after fibroid surgery without a fever?

Yes. An infection may cause local redness, swelling, increasing pain, or unusual drainage without a noticeable fever. Some internal infections may also lack obvious wound changes. Contact your surgical team if you develop concerning or worsening symptoms, even if your temperature is normal.

Is vaginal discharge normal after fibroid surgery?

Light spotting or some vaginal discharge may occur after certain fibroid procedures. Discharge that becomes foul-smelling, changes significantly in appearance, or occurs with fever or worsening pelvic pain needs medical assessment. Heavy bleeding should also be reported promptly.

How long after fibroid surgery can an infection develop?

An infection may become apparent in the first few days or later during recovery. Many surgical wound infections occur within 30 days of surgery, although this general timeframe does not predict when an individual infection will develop. Report new or worsening symptoms whenever they occur.

Does worsening pain always mean there is an infection?

No. Worsening pain can have several causes, including complications that are not infections. However, pain that becomes severe, increases instead of improving, or occurs with fever, abnormal discharge, or wound changes needs prompt medical assessment.

Can an infection after fibroid surgery be treated?

Many postoperative infections can be treated, but the appropriate care depends on the location and extent of the infection. A healthcare professional may recommend antibiotics or additional treatment based on the findings. Early assessment helps determine the appropriate next steps and identify complications that require urgent care.

Citations

  1. MedlinePlus Medical Encyclopedia: Surgical Wound Infection
  2. MedlinePlus Medical Encyclopedia: Surgical Wound Care — Closed
  3. University College London Hospitals NHS Foundation Trust: Preparing for Gynaecology Surgery and Your Recovery
  4. American College of Obstetricians and Gynecologists: Laparoscopy
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