MedChunk
Medically reviewed

Is Adenomyosis a Form of Endometriosis?

Learn whether adenomyosis is a form of endometriosis, how the two conditions differ, their shared symptoms, diagnosis, and treatment options for patients.

By Caleb Bennett Reviewed by Dr. Irene Medical review dateNov 8, 2025 10 min read

No, adenomyosis is not a form of endometriosis. Although both conditions involve tissue similar to the lining of the uterus, they affect different areas. In adenomyosis, this tissue grows into the muscular wall of the uterus. In endometriosis, similar tissue grows outside the uterus, often on the ovaries, fallopian tubes, or other pelvic structures. Both conditions can cause painful periods and pelvic pain, and they can occur together.

How Are Adenomyosis and Endometriosis Different?

The main difference between adenomyosis and endometriosis is where the tissue grows. Both conditions involve endometrial-like tissue, but their locations within the body distinguish them. According to the Cleveland Clinic, adenomyosis affects the muscle of the uterus, whereas endometriosis involves tissue growing outside the uterus.

This difference matters because the conditions can affect menstrual bleeding, pelvic pain, fertility, and treatment decisions in different ways. Their symptoms can overlap, so the type and timing of symptoms alone may not establish which condition is present.

Adenomyosis: Tissue Growing Into the Uterine Muscle

The uterus has an inner lining called the endometrium and a muscular wall called the myometrium. In adenomyosis, tissue resembling the uterine lining grows into the muscular wall. This can cause the uterus to become enlarged or tender and may contribute to painful periods and heavy menstrual bleeding.

Adenomyosis can occur without noticeable symptoms. When symptoms develop, they may affect menstrual bleeding and cause discomfort in the lower abdomen or pelvis. The condition is more commonly diagnosed in people over 30, although it can affect anyone who has periods.

Endometriosis: Tissue Growing Outside the Uterus

Endometriosis occurs when tissue similar to the uterine lining grows outside the uterus. It commonly affects the ovaries, fallopian tubes, and tissues lining the pelvis. In some cases, it involves the bowel, bladder, or other areas.

According to Mayo Clinic, this tissue responds to hormonal changes during the menstrual cycle. It can contribute to inflammation, pain, and scar tissue formation. When the ovaries are affected, endometriosis can also cause cysts known as endometriomas.

Can Adenomyosis and Endometriosis Occur Together?

Yes. A person can have both adenomyosis and endometriosis at the same time. Although they are separate conditions, they share some features and may contribute to overlapping symptoms, including painful periods and ongoing pelvic pain.

Having one condition does not automatically mean that the other is present. However, when symptoms persist despite treatment or the explanation for pelvic pain remains unclear, a healthcare professional may consider whether more than one condition could be contributing.

Distinguishing between the two can help guide further assessment and treatment. For example, symptoms associated with heavy menstrual bleeding may lead a clinician to investigate adenomyosis, while pain related to bowel movements or sexual intercourse may prompt consideration of endometriosis. These patterns are clues for clinical assessment, not definitive ways to identify either condition.

What Symptoms Do the Two Conditions Share?

Adenomyosis and endometriosis can both cause menstrual pain and pelvic discomfort. However, the pattern of bleeding and the location of pain may differ. Some people experience significant symptoms, while others have few or none.

Symptoms that may occur with adenomyosis include:

  • Heavy or prolonged menstrual bleeding.
  • Painful menstrual cramps.
  • Pelvic pain or tenderness.
  • A feeling of pressure, fullness, or heaviness in the lower abdomen.
  • Pain during sexual intercourse.

Symptoms that may occur with endometriosis include:

  • Painful periods that may interfere with daily activities.
  • Pelvic pain that occurs during or outside menstruation.
  • Pain during or after sexual intercourse.
  • Pain during bowel movements or urination, particularly around menstruation.
  • Difficulty becoming pregnant in some cases.

Heavy menstrual bleeding is often associated with adenomyosis, while endometriosis is commonly associated with pelvic pain and may involve pain during bowel movements or urination. Neither pattern is exclusive to one condition, and symptoms can overlap.

How Are Adenomyosis and Endometriosis Diagnosed?

Because the symptoms can be similar, healthcare professionals consider the full clinical picture rather than relying on a single symptom. This assessment may include menstrual history, pain patterns, a physical or pelvic examination when appropriate, and imaging tests.

Diagnosing Adenomyosis

Adenomyosis is commonly evaluated using pelvic imaging. According to the NHS, an ultrasound scan or magnetic resonance imaging (MRI) may be used to investigate the condition. These tests can help clinicians examine the uterus and look for changes in its muscular wall.

The choice of test depends on the symptoms and clinical findings. Imaging may also help identify other possible causes of heavy bleeding or pelvic pain, such as uterine fibroids. The results are interpreted alongside the person's medical history and examination findings.

Diagnosing Endometriosis

Endometriosis assessment may also involve a pelvic examination, ultrasound, or MRI. These tests can help identify certain forms of endometriosis and related changes, including ovarian endometriomas. However, a normal scan does not rule out every form of the condition.

According to the American College of Obstetricians and Gynecologists (ACOG), laparoscopy, a surgical procedure that allows a clinician to examine the pelvic cavity, may be used to confirm endometriosis. The need for surgery depends on the individual circumstances; assessment and treatment planning can begin with symptoms, examination, and imaging.

Do Adenomyosis and Endometriosis Have Different Treatments?

Yes. Although some treatment approaches overlap, care is tailored to the condition being treated, the symptoms involved, the person's medical history, and whether they wish to become pregnant in the future.

Treatment options for adenomyosis may include:

  • Anti-inflammatory pain medicines to help relieve menstrual cramps.
  • Hormonal contraception or a hormonal intrauterine system to reduce bleeding and pain.
  • Other medicines to manage heavy menstrual bleeding when appropriate.
  • Surgery, including hysterectomy in selected cases when other approaches are unsuitable or unsuccessful and future pregnancy is not desired.

Management of endometriosis may include:

  • Pain-relieving medicines to help manage discomfort.
  • Hormonal treatments to reduce the activity of endometriosis and help control symptoms.
  • Surgery to remove endometriosis tissue when appropriate.
  • Individualized fertility assessment and treatment when pregnancy is a concern.

Some medicines can help manage symptoms of both conditions, but treatment outcomes vary. A treatment that reduces menstrual bleeding may not adequately address pain caused by endometriosis outside the uterus. Likewise, treatment decisions for someone with both conditions may need to account for symptoms arising from each one.

Can Either Condition Affect Fertility?

Both adenomyosis and endometriosis may be associated with fertility difficulties, but neither condition means that pregnancy is impossible. The effect on fertility varies from person to person and depends on individual clinical factors.

Endometriosis can involve the ovaries, fallopian tubes, and surrounding pelvic tissues, potentially affecting reproductive function. Adenomyosis affects the uterine muscle and may also be associated with difficulties conceiving or pregnancy complications. The presence of either condition alone does not predict an individual's ability to become pregnant.

If pregnancy is a priority, it is helpful to discuss fertility goals before starting treatment. Some hormonal treatments prevent pregnancy while they are being used, and surgical decisions can have lasting consequences for fertility. A gynecologist can explain which options are appropriate for the person's circumstances.

When Should You Seek Medical Advice?

Consider arranging an appointment with a healthcare professional if menstrual pain is persistent, bleeding is unusually heavy or prolonged, pelvic pain is worsening, or symptoms interfere with work, school, sleep, or daily activities. Assessment is also appropriate when painful periods occur alongside bowel or bladder symptoms, pain during sex, or concerns about fertility.

Very heavy bleeding accompanied by faintness, severe weakness, or shortness of breath warrants urgent medical assessment. Sudden, severe pelvic pain also requires prompt evaluation, particularly if pregnancy is possible.

Keeping a record of menstrual dates, bleeding patterns, pain, and other symptoms may help a clinician understand the problem. The goal is to identify the likely cause or causes and choose an appropriate approach to care.

What Is the Main Takeaway?

Adenomyosis is not a form of endometriosis, but the two conditions are closely related in the sense that both involve tissue resembling the uterine lining. Adenomyosis affects the muscle within the uterus, while endometriosis affects areas outside it. They can cause similar symptoms and may occur together, but their diagnosis and management are not identical. Understanding the difference can help patients have more informed conversations with their healthcare professionals about evaluation, treatment, and fertility goals.

Frequently Asked Questions

Answers to common questions about the relationship between adenomyosis and endometriosis.

Is adenomyosis considered a type of endometriosis?

No. Adenomyosis and endometriosis are separate conditions. Adenomyosis involves endometrial-like tissue within the muscular wall of the uterus, whereas endometriosis involves similar tissue outside the uterus. Both can cause pelvic pain and painful periods, and they can occur together.

Which is worse, adenomyosis or endometriosis?

Neither condition is always worse than the other. Their effects depend on the symptoms, their impact on daily life, and individual clinical circumstances. Adenomyosis is often associated with heavy menstrual bleeding, while endometriosis may cause pelvic pain and symptoms involving nearby organs. Either condition can significantly affect quality of life.

Can an ultrasound tell the difference between adenomyosis and endometriosis?

An ultrasound can help identify features of adenomyosis and certain forms of endometriosis, including ovarian endometriomas. However, not all endometriosis is visible on imaging. Clinicians interpret scan findings alongside symptoms, medical history, and other examination results to determine the next steps.

Can you have adenomyosis without endometriosis?

Yes. Adenomyosis can occur on its own, without endometriosis. The two conditions may coexist, but a diagnosis of one does not automatically establish the presence of the other. The appropriate evaluation depends on the symptoms and clinical findings.

Can adenomyosis turn into endometriosis?

Adenomyosis is not generally understood as a condition that turns into endometriosis. They are distinct disorders defined by the location of endometrial-like tissue. A person may have both conditions, but their coexistence does not mean one has developed from the other.

Citations

  1. Cleveland Clinic: Adenomyosis — Causes, Symptoms, Diagnosis and Treatment
  2. Mayo Clinic: Endometriosis — Symptoms and Causes
  3. NHS: Adenomyosis
  4. American College of Obstetricians and Gynecologists: Endometriosis
Share this article