What causes high Alkaline phosphatase and low Bilirubin direct?

High Alkaline phosphatase and low Bilirubin direct can be caused by many reasons.

If your Alkaline phosphatase is in between 30 U/L and 120 U/L and your Bilirubin direct is in between 0.1 mg/dL and 0.2 mg/dL then you need not worry as these are the normal ranges for Alkaline phosphatase and Bilirubin direct respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease Alkaline phosphatase levels include:

• Alcohol abuse
• Ulcerative colitis
• Blockage of the bile ducts.
• Insulin resistance
• Congestive heart failure

Alkaline phosphatase treatment - Click to read 10 GOLDEN ARTICLES on Liver health

Normal range of Alkaline phosphatase : 30 - 120 U/L

Ideal values of Alkaline phosphatase depending on age :

Age	Ideal Alkaline phosphatase value
<5 years	30.516
5-10 years	31.041
10-15 years	31.575
15-20 years	32.118
20-25 years	32.67
25-30 years	33.232
30-35 years	33.804
35-40 years	34.385
40-45 years	34.976
45-50 years	35.578
50-55 years	36.19
55-60 years	36.812
60-70 years	37.445
70-80 years	38.089
80-90 years	38.744
90-100 years	39.41
>100 years	40.088

*Ideal values are calculated based on our database of patient records

Normal range of Bilirubin direct : 0.1 - 0.2 mg/dL

Ideal values of Bilirubin direct depending on age :

Age	Ideal Bilirubin direct value
<5 years	0.11189
5-10 years	0.11381
10-15 years	0.11577
15-20 years	0.11776
20-25 years	0.11979
25-30 years	0.12185
30-35 years	0.12395
35-40 years	0.12608
40-45 years	0.12825
45-50 years	0.13046
50-55 years	0.1327
55-60 years	0.13498
60-70 years	0.1373
70-80 years	0.13966
80-90 years	0.14206
90-100 years	0.1445
>100 years	0.14699

High Alkaline phosphatase and low Bilirubin direct can be caused by a lot of reasons. If you take Alkaline phosphatase and Bilirubin direct blood tests and the results are higher than 120 U/L for Alkaline phosphatase and lower than 0.1 mg/dL for Bilirubin direct, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the Alkaline phosphatase and Bilirubin direct Tests Are Done :

If your doctor wants Alkaline phosphatase and Bilirubin direct tests on you, you may need to go through these tests. During the Alkaline phosphatase and Bilirubin direct blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your Alkaline phosphatase and Bilirubin direct Test reports by your pathologist.

Medical References

• Cleveland Clinic – Alkaline Phosphatase (ALP): What It Is, Causes & Treatment
• Mayo Clinic – Alkaline phosphatase (ALP) blood test
• MedlinePlus – Alkaline Phosphatase
• WebMD – Alkaline Phosphatase (ALP): Tests and Results