What causes high Alkaline phosphatase and low Prothrombin time?

High Alkaline phosphatase and low Prothrombin time can be caused by many reasons.

If your Alkaline phosphatase is in between 30 U/L and 120 U/L and your Prothrombin time is in between 12 seconds and 16 seconds then you need not worry as these are the normal ranges for Alkaline phosphatase and Prothrombin time respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease Alkaline phosphatase levels include:

• Alcohol abuse
• Ulcerative colitis
• Blockage of the bile ducts.
• Insulin resistance
• Congestive heart failure

Alkaline phosphatase treatment - Click to read 10 GOLDEN ARTICLES on Liver health

Normal range of Alkaline phosphatase : 30 - 120 U/L

Ideal values of Alkaline phosphatase depending on age :

Age	Ideal Alkaline phosphatase value
<5 years	30.53
5-10 years	31.07
10-15 years	31.619
15-20 years	32.178
20-25 years	32.747
25-30 years	33.326
30-35 years	33.915
35-40 years	34.515
40-45 years	35.125
45-50 years	35.746
50-55 years	36.378
55-60 years	37.021
60-70 years	37.676
70-80 years	38.342
80-90 years	39.02
90-100 years	39.71
>100 years	40.412

*Ideal values are calculated based on our database of patient records

Normal range of Prothrombin time : 12 - 16 seconds

Ideal values of Prothrombin time depending on age :

Age	Ideal Prothrombin time value
<5 years	12.212
5-10 years	12.428
10-15 years	12.648
15-20 years	12.872
20-25 years	13.1
25-30 years	13.332
30-35 years	13.568
35-40 years	13.808
40-45 years	14.052
45-50 years	14.3
50-55 years	14.553
55-60 years	14.81
60-70 years	15.072
70-80 years	15.338
80-90 years	15.609
90-100 years	15.885
>100 years	15.88

High Alkaline phosphatase and low Prothrombin time can be caused by a lot of reasons. If you take Alkaline phosphatase and Prothrombin time blood tests and the results are higher than 120 U/L for Alkaline phosphatase and lower than 12 seconds for Prothrombin time, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the Alkaline phosphatase and Prothrombin time Tests Are Done :

If your doctor wants Alkaline phosphatase and Prothrombin time tests on you, you may need to go through these tests. During the Alkaline phosphatase and Prothrombin time blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your Alkaline phosphatase and Prothrombin time Test reports by your pathologist.

Medical References

• Cleveland Clinic – Alkaline Phosphatase (ALP): What It Is, Causes & Treatment
• Mayo Clinic – Alkaline phosphatase (ALP) blood test
• MedlinePlus – Alkaline Phosphatase
• WebMD – Alkaline Phosphatase (ALP): Tests and Results