What causes high APTT and low MCV?

High APTT and low MCV can be caused by many reasons.

If your APTT is in between 22 seconds and 35 seconds and your MCV is in between 83 fL and 101 fL then you need not worry as these are the normal ranges for APTT and MCV respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease APTT levels include:

• Liver disease
• Vitamin K abnormality
• Decreased or defective factor I (fibrinogen), II (prothrombin), V or X
• Hemophilia A and hemophilia B
• Willebrand disease

Normal range of APTT : 22 - 35 seconds

Ideal values of APTT depending on age :

Age	Ideal APTT value
<5 years	22.375
5-10 years	22.756
10-15 years	23.144
15-20 years	23.539
20-25 years	23.94
25-30 years	24.348
30-35 years	24.763
35-40 years	25.185
40-45 years	25.614
45-50 years	26.051
50-55 years	26.495
55-60 years	26.947
60-70 years	27.406
70-80 years	27.873
80-90 years	28.348
90-100 years	28.831
>100 years	29.323

*Ideal values are calculated based on our database of patient records

Normal range of MCV : 83 - 101 fL

Ideal values of MCV depending on age :

Age	Ideal MCV value
<5 years	84.415
5-10 years	85.854
10-15 years	87.318
15-20 years	88.807
20-25 years	90.321
25-30 years	91.861
30-35 years	93.427
35-40 years	95.02
40-45 years	96.64
45-50 years	98.288
50-55 years	99.964
55-60 years	99.935
60-70 years	99.906
70-80 years	99.877
80-90 years	99.848
90-100 years	99.819
>100 years	99.79

High APTT and low MCV can be caused by a lot of reasons. If you take APTT and MCV blood tests and the results are higher than 35 seconds for APTT and lower than 83 fL for MCV, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

This page has got the maximum number of views from the below mentioned cities (traffic in last 30 days):

How the APTT and MCV Tests Are Done :

If your doctor wants APTT and MCV tests on you, you may need to go through these tests. During the APTT and MCV blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your APTT and MCV Test reports by your pathologist.

Medical References

• WebMD – Activated Partial Thromboplastin Time (APTT) Test
• Cleveland Clinic – Partial Thromboplastin Time (PTT) Test
• NIH – Solutions to Establishing and Verifying Normal Reference Intervals and Assessing APTT Reagents