What causes high Bilirubin indirect and low Alkaline phosphatase?

High Bilirubin indirect and low Alkaline phosphatase can be caused by many reasons.

If your Bilirubin indirect is in between 0.1 mg/dL and 1 mg/dL and your Alkaline phosphatase is in between 30 U/L and 120 U/L then you need not worry as these are the normal ranges for Bilirubin indirect and Alkaline phosphatase respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease Bilirubin levels include:

• Gallstones present in the bile ducts
• Hepatitis A, hepatitis B, hepatitis C
• Scarring of the bile ducts
• Lack of oxygen (hypoxia)
• Liver disease

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Normal range of Bilirubin indirect : 0.1 - 1 mg/dL

Ideal values of Bilirubin indirect depending on age :

Age	Ideal Bilirubin indirect value
<5 years	0.1088
5-10 years	0.11837
10-15 years	0.12879
15-20 years	0.14012
20-25 years	0.15245
25-30 years	0.16587
30-35 years	0.18047
35-40 years	0.19635
40-45 years	0.21363
45-50 years	0.23243
50-55 years	0.25288
55-60 years	0.27513
60-70 years	0.29934
70-80 years	0.32568
80-90 years	0.35434
90-100 years	0.38552
>100 years	0.41945

*Ideal values are calculated based on our database of patient records

Normal range of Alkaline phosphatase : 30 - 120 U/L

Ideal values of Alkaline phosphatase depending on age :

Age	Ideal Alkaline phosphatase value
<5 years	32.64
5-10 years	35.512
10-15 years	38.637
15-20 years	42.037
20-25 years	45.736
25-30 years	49.761
30-35 years	54.14
35-40 years	58.904
40-45 years	64.088
45-50 years	69.728
50-55 years	75.864
55-60 years	82.54
60-70 years	89.804
70-80 years	97.707
80-90 years	106.305
90-100 years	115.66
>100 years	114.764

High Bilirubin indirect and low Alkaline phosphatase can be caused by a lot of reasons. If you take Bilirubin indirect and Alkaline phosphatase blood tests and the results are higher than 1 mg/dL for Bilirubin indirect and lower than 30 U/L for Alkaline phosphatase, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the Bilirubin indirect and Alkaline phosphatase Tests Are Done :

If your doctor wants Bilirubin indirect and Alkaline phosphatase tests on you, you may need to go through these tests. During the Bilirubin indirect and Alkaline phosphatase blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your Bilirubin indirect and Alkaline phosphatase Test reports by your pathologist.

Medical References

• Cleveland Clinic – Bilirubin Test: Understanding High vs. Low Levels & Causes
• Mayo Clinic – Bilirubin test
• MedlinePlus – Bilirubin Blood Test
• WebMD – Bilirubin Test: High vs. Low Levels, Direct vs. Indirect
• NIH – Physiology, Bilirubin