What causes high Globulin and low Vitamin B12?

High Globulin and low Vitamin B12 can be caused by many reasons.

If your Globulin is in between 2 g/dL and 4.1 g/dL and your Vitamin B12 is in between 211 pg/mL and 911 pg/mL then you need not worry as these are the normal ranges for Globulin and Vitamin B12 respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease Globulin levels include:

• Liver disease
• Kidney disease
• Lupus
• Rheumatoid arthritis
• Hemolytic anemia

Globulin treatment - Click to read 10 GOLDEN ARTICLES on Liver health

Normal range of Globulin : 2 - 4.1 g/dL

Ideal values of Globulin depending on age :

Age	Ideal Globulin value
<5 years	2.031
5-10 years	2.062
10-15 years	2.094
15-20 years	2.126
20-25 years	2.159
25-30 years	2.192
30-35 years	2.226
35-40 years	2.26
40-45 years	2.295
45-50 years	2.33
50-55 years	2.366
55-60 years	2.402
60-70 years	2.439
70-80 years	2.477
80-90 years	2.515
90-100 years	2.554
>100 years	2.593

*Ideal values are calculated based on our database of patient records

Normal range of Vitamin B12 : 211 - 911 pg/mL

Ideal values of Vitamin B12 depending on age :

Age	Ideal Vitamin B12 value
<5 years	214.249
5-10 years	217.548
10-15 years	220.898
15-20 years	224.3
20-25 years	227.754
25-30 years	231.261
30-35 years	234.822
35-40 years	238.438
40-45 years	242.11
45-50 years	245.838
50-55 years	249.624
55-60 years	253.468
60-70 years	257.371
70-80 years	261.335
80-90 years	265.36
90-100 years	269.447
>100 years	273.596

High Globulin and low Vitamin B12 can be caused by a lot of reasons. If you take Globulin and Vitamin B12 blood tests and the results are higher than 4.1 g/dL for Globulin and lower than 211 pg/mL for Vitamin B12, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the Globulin and Vitamin B12 Tests Are Done :

If your doctor wants Globulin and Vitamin B12 tests on you, you may need to go through these tests. During the Globulin and Vitamin B12 blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your Globulin and Vitamin B12 Test reports by your pathologist.

Medical References

• MedlinePlus – Globulin Test
• Cleveland Clinic – Globulin Blood Test: What It Is, Procedure, Results
• WebMD – Total Serum Protein Test & Albumin to Globulin (A/G) Ratio