What causes high INR and low ALT SGPT?

High INR and low ALT SGPT can be caused by many reasons.

If your INR is in between 0.9 ratio and 1.2 ratio and your ALT SGPT is in between 21 U/L and 72 U/L then you need not worry as these are the normal ranges for INR and ALT SGPT respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease INR levels include:

• Liver disease
• Vitamin K abnormality
• Decreased or defective factor I (fibrinogen), II (prothrombin), V or X
• Hemophilia A and hemophilia B
• Autoantibody against a specific factor (e.g., factor VIII)

Normal range of INR : 0.9 - 1.2 ratio

Ideal values of INR depending on age :

Age	Ideal INR value
<5 years	0.947
5-10 years	0.997
10-15 years	1.05
15-20 years	1.105
20-25 years	1.163
25-30 years	1.159
30-35 years	1.156
35-40 years	1.153
40-45 years	1.15
45-50 years	1.147
50-55 years	1.143
55-60 years	1.14
60-70 years	1.2
70-80 years	1.196
80-90 years	1.193
90-100 years	1.19
>100 years	1.187

*Ideal values are calculated based on our database of patient records

Normal range of ALT SGPT : 21 - 72 U/L

Ideal values of ALT SGPT depending on age :

Age	Ideal ALT SGPT value
<5 years	22.107
5-10 years	23.272
10-15 years	24.498
15-20 years	25.789
20-25 years	27.148
25-30 years	28.579
30-35 years	30.085
35-40 years	31.67
40-45 years	33.339
45-50 years	35.096
50-55 years	36.946
55-60 years	38.893
60-70 years	40.943
70-80 years	43.101
80-90 years	45.372
90-100 years	47.763
>100 years	50.28

High INR and low ALT SGPT can be caused by a lot of reasons. If you take INR and ALT SGPT blood tests and the results are higher than 1.2 ratio for INR and lower than 21 U/L for ALT SGPT, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the INR and ALT SGPT Tests Are Done :

If your doctor wants INR and ALT SGPT tests on you, you may need to go through these tests. During the INR and ALT SGPT blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your INR and ALT SGPT Test reports by your pathologist.

Medical References

• MedlinePlus – Prothrombin Time Test and INR (PT/INR)
• Mayo Clinic – Prothrombin time test
• Cleveland Clinic – Prothrombin Time (PT/INR) Test