What causes high INR and low Globulin?

High INR and low Globulin can be caused by many reasons.

If your INR is in between 0.9 ratio and 1.2 ratio and your Globulin is in between 2 g/dL and 4.1 g/dL then you need not worry as these are the normal ranges for INR and Globulin respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease INR levels include:

• Liver disease
• Vitamin K abnormality
• Decreased or defective factor I (fibrinogen), II (prothrombin), V or X
• Hemophilia A and hemophilia B
• Autoantibody against a specific factor (e.g., factor VIII)

Normal range of INR : 0.9 - 1.2 ratio

Ideal values of INR depending on age :

Age	Ideal INR value
<5 years	0.947
5-10 years	0.997
10-15 years	1.049
15-20 years	1.104
20-25 years	1.162
25-30 years	1.159
30-35 years	1.156
35-40 years	1.153
40-45 years	1.149
45-50 years	1.146
50-55 years	1.143
55-60 years	1.14
60-70 years	1.2
70-80 years	1.197
80-90 years	1.194
90-100 years	1.191
>100 years	1.187

*Ideal values are calculated based on our database of patient records

Normal range of Globulin : 2 - 4.1 g/dL

Ideal values of Globulin depending on age :

Age	Ideal Globulin value
<5 years	2.105
5-10 years	2.215
10-15 years	2.331
15-20 years	2.453
20-25 years	2.582
25-30 years	2.717
30-35 years	2.859
35-40 years	3.009
40-45 years	3.167
45-50 years	3.333
50-55 years	3.508
55-60 years	3.692
60-70 years	3.885
70-80 years	4.089
80-90 years	4.078
90-100 years	4.067
>100 years	4.056

High INR and low Globulin can be caused by a lot of reasons. If you take INR and Globulin blood tests and the results are higher than 1.2 ratio for INR and lower than 2 g/dL for Globulin, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the INR and Globulin Tests Are Done :

If your doctor wants INR and Globulin tests on you, you may need to go through these tests. During the INR and Globulin blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your INR and Globulin Test reports by your pathologist.

Medical References

• MedlinePlus – Prothrombin Time Test and INR (PT/INR)
• Mayo Clinic – Prothrombin time test
• Cleveland Clinic – Prothrombin Time (PT/INR) Test