What causes high INR and low Packed cell volume?

High INR and low Packed cell volume can be caused by many reasons.

If your INR is in between 0.9 ratio and 1.2 ratio and your Packed cell volume is in between 41 % and 49.5 % then you need not worry as these are the normal ranges for INR and Packed cell volume respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease INR levels include:

• Liver disease
• Vitamin K abnormality
• Decreased or defective factor I (fibrinogen), II (prothrombin), V or X
• Hemophilia A and hemophilia B
• Autoantibody against a specific factor (e.g., factor VIII)

Normal range of INR : 0.9 - 1.2 ratio

Ideal values of INR depending on age :

Age	Ideal INR value
<5 years	0.951
5-10 years	1.004
10-15 years	1.06
15-20 years	1.12
20-25 years	1.183
25-30 years	1.179
30-35 years	1.175
35-40 years	1.171
40-45 years	1.167
45-50 years	1.164
50-55 years	1.16
55-60 years	1.156
60-70 years	1.152
70-80 years	1.149
80-90 years	1.146
90-100 years	1.142
>100 years	1.138

*Ideal values are calculated based on our database of patient records

Normal range of Packed cell volume : 41 - 49.5 %

Ideal values of Packed cell volume depending on age :

Age	Ideal Packed cell volume value
<5 years	43.304
5-10 years	45.738
10-15 years	48.308
15-20 years	48.156
20-25 years	48.004
25-30 years	47.853
30-35 years	47.702
35-40 years	47.551
40-45 years	47.4
45-50 years	47.25
50-55 years	47.1
55-60 years	46.951
60-70 years	46.803
70-80 years	49.433
80-90 years	49.277
90-100 years	49.121
>100 years	48.966

High INR and low Packed cell volume can be caused by a lot of reasons. If you take INR and Packed cell volume blood tests and the results are higher than 1.2 ratio for INR and lower than 41 % for Packed cell volume, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the INR and Packed cell volume Tests Are Done :

If your doctor wants INR and Packed cell volume tests on you, you may need to go through these tests. During the INR and Packed cell volume blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your INR and Packed cell volume Test reports by your pathologist.

Medical References

• MedlinePlus – Prothrombin Time Test and INR (PT/INR)
• Mayo Clinic – Prothrombin time test
• Cleveland Clinic – Prothrombin Time (PT/INR) Test