What causes high INR and low Thrombin Time?

High INR and low Thrombin Time can be caused by many reasons.

If your INR is in between 0.9 ratio and 1.2 ratio and your Thrombin Time is in between 14 sec and 23 sec then you need not worry as these are the normal ranges for INR and Thrombin Time respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease INR levels include:

• Liver disease
• Vitamin K abnormality
• Decreased or defective factor I (fibrinogen), II (prothrombin), V or X
• Hemophilia A and hemophilia B
• Autoantibody against a specific factor (e.g., factor VIII)

Normal range of INR : 0.9 - 1.2 ratio

Ideal values of INR depending on age :

Age	Ideal INR value
<5 years	0.952
5-10 years	1.007
10-15 years	1.065
15-20 years	1.126
20-25 years	1.191
25-30 years	1.187
30-35 years	1.183
35-40 years	1.179
40-45 years	1.175
45-50 years	1.172
50-55 years	1.168
55-60 years	1.164
60-70 years	1.16
70-80 years	1.156
80-90 years	1.152
90-100 years	1.148
>100 years	1.144

*Ideal values are calculated based on our database of patient records

Normal range of Thrombin Time : 14 - 23 sec

Ideal values of Thrombin Time depending on age :

Age	Ideal Thrombin Time value
<5 years	1.058
5-10 years	1.058
10-15 years	1.058
15-20 years	1.058
20-25 years	1.058
25-30 years	1.058
30-35 years	1.058
35-40 years	1.058
40-45 years	1.058
45-50 years	1.058
50-55 years	1.058
55-60 years	1.058
60-70 years	1.058
70-80 years	1.058
80-90 years	1.058
90-100 years	1.058
>100 years	1.058

High INR and low Thrombin Time can be caused by a lot of reasons. If you take INR and Thrombin Time blood tests and the results are higher than 1.2 ratio for INR and lower than 14 sec for Thrombin Time, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the INR and Thrombin Time Tests Are Done :

If your doctor wants INR and Thrombin Time tests on you, you may need to go through these tests. During the INR and Thrombin Time blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your INR and Thrombin Time Test reports by your pathologist.

Medical References

• MedlinePlus – Prothrombin Time Test and INR (PT/INR)
• Mayo Clinic – Prothrombin time test
• Cleveland Clinic – Prothrombin Time (PT/INR) Test