What causes high INR and low Total serum iron?

High INR and low Total serum iron can be caused by many reasons.

If your INR is in between 0.9 ratio and 1.2 ratio and your Total serum iron is in between 40 mcg/dL and 190 mcg/dL then you need not worry as these are the normal ranges for INR and Total serum iron respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease INR levels include:

• Liver disease
• Vitamin K abnormality
• Decreased or defective factor I (fibrinogen), II (prothrombin), V or X
• Hemophilia A and hemophilia B
• Autoantibody against a specific factor (e.g., factor VIII)

Normal range of INR : 0.9 - 1.2 ratio

Ideal values of INR depending on age :

Age	Ideal INR value
<5 years	0.951
5-10 years	1.005
10-15 years	1.062
15-20 years	1.123
20-25 years	1.187
25-30 years	1.183
30-35 years	1.179
35-40 years	1.175
40-45 years	1.171
45-50 years	1.167
50-55 years	1.163
55-60 years	1.16
60-70 years	1.156
70-80 years	1.152
80-90 years	1.148
90-100 years	1.145
>100 years	1.141

*Ideal values are calculated based on our database of patient records

Normal range of Total serum iron : 40 - 190 mcg/dL

Ideal values of Total serum iron depending on age :

Age	Ideal Total serum iron value
<5 years	42.288
5-10 years	44.707
10-15 years	47.264
15-20 years	49.968
20-25 years	52.826
25-30 years	55.848
30-35 years	59.043
35-40 years	62.42
40-45 years	65.99
45-50 years	69.765
50-55 years	73.756
55-60 years	77.975
60-70 years	82.435
70-80 years	87.15
80-90 years	92.135
90-100 years	97.405
>100 years	102.977

High INR and low Total serum iron can be caused by a lot of reasons. If you take INR and Total serum iron blood tests and the results are higher than 1.2 ratio for INR and lower than 40 mcg/dL for Total serum iron, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the INR and Total serum iron Tests Are Done :

If your doctor wants INR and Total serum iron tests on you, you may need to go through these tests. During the INR and Total serum iron blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your INR and Total serum iron Test reports by your pathologist.

Medical References

• MedlinePlus – Prothrombin Time Test and INR (PT/INR)
• Mayo Clinic – Prothrombin time test
• Cleveland Clinic – Prothrombin Time (PT/INR) Test