What causes high INR and low Transferrin saturation?

High INR and low Transferrin saturation can be caused by many reasons.

If your INR is in between 0.9 ratio and 1.2 ratio and your Transferrin saturation is in between 13 % and 45 % then you need not worry as these are the normal ranges for INR and Transferrin saturation respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease INR levels include:

• Liver disease
• Vitamin K abnormality
• Decreased or defective factor I (fibrinogen), II (prothrombin), V or X
• Hemophilia A and hemophilia B
• Autoantibody against a specific factor (e.g., factor VIII)

Normal range of INR : 0.9 - 1.2 ratio

Ideal values of INR depending on age :

Age	Ideal INR value
<5 years	0.952
5-10 years	1.007
10-15 years	1.065
15-20 years	1.126
20-25 years	1.191
25-30 years	1.187
30-35 years	1.183
35-40 years	1.179
40-45 years	1.176
45-50 years	1.172
50-55 years	1.168
55-60 years	1.164
60-70 years	1.16
70-80 years	1.156
80-90 years	1.152
90-100 years	1.148
>100 years	1.144

*Ideal values are calculated based on our database of patient records

Normal range of Transferrin saturation : 13 - 45 %

Ideal values of Transferrin saturation depending on age :

Age	Ideal Transferrin saturation value
<5 years	13.745
5-10 years	14.533
10-15 years	15.366
15-20 years	16.246
20-25 years	17.177
25-30 years	18.161
30-35 years	19.202
35-40 years	20.302
40-45 years	21.465
45-50 years	22.695
50-55 years	23.995
55-60 years	25.37
60-70 years	26.824
70-80 years	28.361
80-90 years	29.986
90-100 years	31.704
>100 years	33.521

High INR and low Transferrin saturation can be caused by a lot of reasons. If you take INR and Transferrin saturation blood tests and the results are higher than 1.2 ratio for INR and lower than 13 % for Transferrin saturation, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the INR and Transferrin saturation Tests Are Done :

If your doctor wants INR and Transferrin saturation tests on you, you may need to go through these tests. During the INR and Transferrin saturation blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your INR and Transferrin saturation Test reports by your pathologist.

Medical References

• MedlinePlus – Prothrombin Time Test and INR (PT/INR)
• Mayo Clinic – Prothrombin time test
• Cleveland Clinic – Prothrombin Time (PT/INR) Test