What causes high MPV and low Prothrombin time?

High MPV and low Prothrombin time can be caused by many reasons.

If your MPV is in between 6.8 fL and 10.9 fL and your Prothrombin time is in between 12 seconds and 16 seconds then you need not worry as these are the normal ranges for MPV and Prothrombin time respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease MPV levels include:

• Primary or secondary thrombocytosis
• Marrow hypoplasia.
• Heart disease
• Autoimmune diseases
• Atrial fibrillation, irregular heartbeat

Normal range of Prothrombin time : 12 - 16 seconds

Ideal values of Prothrombin time depending on age :

Age	Ideal Prothrombin time value
<5 years	12.322
5-10 years	12.652
10-15 years	12.991
15-20 years	13.339
20-25 years	13.696
25-30 years	14.063
30-35 years	14.44
35-40 years	14.827
40-45 years	15.224
45-50 years	15.632
50-55 years	15.621
55-60 years	15.61
60-70 years	15.598
70-80 years	15.587
80-90 years	15.576
90-100 years	15.993
>100 years	15.982

High MPV and low Prothrombin time can be caused by a lot of reasons. If you take MPV and Prothrombin time blood tests and the results are higher than 10.9 fL for MPV and lower than 12 seconds for Prothrombin time, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the MPV and Prothrombin time Tests Are Done :

If your doctor wants MPV and Prothrombin time tests on you, you may need to go through these tests. During the MPV and Prothrombin time blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your MPV and Prothrombin time Test reports by your pathologist.

Medical References

• Cleveland Clinic – MPV Blood Test
• MedlinePlus – MPV Blood Test
• Verywell Health – MPV Blood Test: What Low and High Test Results Mean
• PubMed – What a Family Doctor Should Know about Incidental Finding of High Mean Platelet Volume
• Health.com – Understanding Your Mean Platelet Volume (MPV) Blood Test