What causes high MPV and low RBC?

High MPV and low RBC can be caused by many reasons.

If your MPV is in between 6.8 fL and 10.9 fL and your RBC is in between 4.5 mil/uL and 5.5 mil/uL then you need not worry as these are the normal ranges for MPV and RBC respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease MPV levels include:

• Primary or secondary thrombocytosis
• Marrow hypoplasia.
• Heart disease
• Autoimmune diseases
• Atrial fibrillation, irregular heartbeat

Normal range of RBC : 4.5 - 5.5 mil/uL

Ideal values of RBC depending on age :

Age	Ideal RBC value
<5 years	4.59
5-10 years	4.682
10-15 years	4.776
15-20 years	4.872
20-25 years	4.97
25-30 years	5.07
30-35 years	5.172
35-40 years	5.276
40-45 years	5.382
45-50 years	5.49
50-55 years	5.487
55-60 years	5.485
60-70 years	5.483
70-80 years	5.481
80-90 years	5.479
90-100 years	5.477
>100 years	5.475

High MPV and low RBC can be caused by a lot of reasons. If you take MPV and RBC blood tests and the results are higher than 10.9 fL for MPV and lower than 4.5 mil/uL for RBC, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the MPV and RBC Tests Are Done :

If your doctor wants MPV and RBC tests on you, you may need to go through these tests. During the MPV and RBC blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your MPV and RBC Test reports by your pathologist.

Medical References

• Cleveland Clinic – MPV Blood Test
• MedlinePlus – MPV Blood Test
• Verywell Health – MPV Blood Test: What Low and High Test Results Mean
• PubMed – What a Family Doctor Should Know about Incidental Finding of High Mean Platelet Volume
• Health.com – Understanding Your Mean Platelet Volume (MPV) Blood Test