What causes high Prothrombin time and low CRP?

High Prothrombin time and low CRP can be caused by many reasons.

If your Prothrombin time is in between 12 seconds and 16 seconds and your CRP is in between 0.1 mg/L and 3 mg/L then you need not worry as these are the normal ranges for Prothrombin time and CRP respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease Prothrombin time levels include:

• Liver disease
• Vitamin K abnormality
• Hemophilia A and hemophilia B
• Decreased or defective factor I (fibrinogen), II (prothrombin), V or X
• Willebrand disease

Normal range of Prothrombin time : 12 - 16 seconds

Ideal values of Prothrombin time depending on age :

Age	Ideal Prothrombin time value
<5 years	12.126
5-10 years	12.254
10-15 years	12.383
15-20 years	12.513
20-25 years	12.645
25-30 years	12.778
30-35 years	12.913
35-40 years	13.049
40-45 years	13.186
45-50 years	13.325
50-55 years	13.465
55-60 years	13.607
60-70 years	13.75
70-80 years	13.895
80-90 years	14.041
90-100 years	14.189
>100 years	14.338

*Ideal values are calculated based on our database of patient records

Normal range of CRP : 0.1 - 3 mg/L

Ideal values of CRP depending on age :

Age	Ideal CRP value
<5 years	0.11116
5-10 years	0.11233
10-15 years	0.11351
15-20 years	0.11471
20-25 years	0.11592
25-30 years	0.11714
30-35 years	0.11837
35-40 years	0.11962
40-45 years	0.12088
45-50 years	0.12215
50-55 years	0.12344
55-60 years	0.12474
60-70 years	0.12605
70-80 years	0.12738
80-90 years	0.12872
90-100 years	0.13008
>100 years	0.13145

High Prothrombin time and low CRP can be caused by a lot of reasons. If you take Prothrombin time and CRP blood tests and the results are higher than 16 seconds for Prothrombin time and lower than 0.1 mg/L for CRP, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the Prothrombin time and CRP Tests Are Done :

If your doctor wants Prothrombin time and CRP tests on you, you may need to go through these tests. During the Prothrombin time and CRP blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your Prothrombin time and CRP Test reports by your pathologist.

Medical References

• MedlinePlus – Prothrombin Time Test and INR (PT/INR)
• Mayo Clinic – Prothrombin time test
• Cleveland Clinic – Prothrombin Time (PT/INR) Test