What causes high Prothrombin time and low MCHC?

High Prothrombin time and low MCHC can be caused by many reasons.

If your Prothrombin time is in between 12 seconds and 16 seconds and your MCHC is in between 31.5 g/dL and 34.5 g/dL then you need not worry as these are the normal ranges for Prothrombin time and MCHC respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease Prothrombin time levels include:

• Liver disease
• Vitamin K abnormality
• Hemophilia A and hemophilia B
• Decreased or defective factor I (fibrinogen), II (prothrombin), V or X
• Willebrand disease

Normal range of Prothrombin time : 12 - 16 seconds

Ideal values of Prothrombin time depending on age :

Age	Ideal Prothrombin time value
<5 years	12.121
5-10 years	12.243
10-15 years	12.366
15-20 years	12.491
20-25 years	12.617
25-30 years	12.744
30-35 years	12.872
35-40 years	13.002
40-45 years	13.133
45-50 years	13.265
50-55 years	13.399
55-60 years	13.534
60-70 years	13.67
70-80 years	13.808
80-90 years	13.947
90-100 years	14.087
>100 years	14.229

*Ideal values are calculated based on our database of patient records

Normal range of MCHC : 31.5 - 34.5 g/dL

Ideal values of MCHC depending on age :

Age	Ideal MCHC value
<5 years	31.817
5-10 years	32.137
10-15 years	32.461
15-20 years	32.788
20-25 years	33.118
25-30 years	33.451
30-35 years	33.788
35-40 years	34.128
40-45 years	34.472
45-50 years	34.468
50-55 years	34.464
55-60 years	34.46
60-70 years	34.456
70-80 years	34.453
80-90 years	34.45
90-100 years	34.447
>100 years	34.444

High Prothrombin time and low MCHC can be caused by a lot of reasons. If you take Prothrombin time and MCHC blood tests and the results are higher than 16 seconds for Prothrombin time and lower than 31.5 g/dL for MCHC, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the Prothrombin time and MCHC Tests Are Done :

If your doctor wants Prothrombin time and MCHC tests on you, you may need to go through these tests. During the Prothrombin time and MCHC blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your Prothrombin time and MCHC Test reports by your pathologist.

Medical References

• MedlinePlus – Prothrombin Time Test and INR (PT/INR)
• Mayo Clinic – Prothrombin time test
• Cleveland Clinic – Prothrombin Time (PT/INR) Test