What causes high Prothrombin time and low Packed cell volume?

High Prothrombin time and low Packed cell volume can be caused by many reasons.

If your Prothrombin time is in between 12 seconds and 16 seconds and your Packed cell volume is in between 41 % and 49.5 % then you need not worry as these are the normal ranges for Prothrombin time and Packed cell volume respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease Prothrombin time levels include:

• Liver disease
• Vitamin K abnormality
• Hemophilia A and hemophilia B
• Decreased or defective factor I (fibrinogen), II (prothrombin), V or X
• Willebrand disease

Normal range of Prothrombin time : 12 - 16 seconds

Ideal values of Prothrombin time depending on age :

Age	Ideal Prothrombin time value
<5 years	12.127
5-10 years	12.256
10-15 years	12.386
15-20 years	12.518
20-25 years	12.651
25-30 years	12.785
30-35 years	12.921
35-40 years	13.058
40-45 years	13.197
45-50 years	13.337
50-55 years	13.479
55-60 years	13.622
60-70 years	13.767
70-80 years	13.913
80-90 years	14.061
90-100 years	14.21
>100 years	14.361

*Ideal values are calculated based on our database of patient records

Normal range of Packed cell volume : 41 - 49.5 %

Ideal values of Packed cell volume depending on age :

Age	Ideal Packed cell volume value
<5 years	41.435
5-10 years	41.875
10-15 years	42.32
15-20 years	42.769
20-25 years	43.223
25-30 years	43.682
30-35 years	44.146
35-40 years	44.615
40-45 years	45.089
45-50 years	45.568
50-55 years	46.052
55-60 years	46.541
60-70 years	47.035
70-80 years	47.535
80-90 years	48.04
90-100 years	48.55
>100 years	49.066

High Prothrombin time and low Packed cell volume can be caused by a lot of reasons. If you take Prothrombin time and Packed cell volume blood tests and the results are higher than 16 seconds for Prothrombin time and lower than 41 % for Packed cell volume, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the Prothrombin time and Packed cell volume Tests Are Done :

If your doctor wants Prothrombin time and Packed cell volume tests on you, you may need to go through these tests. During the Prothrombin time and Packed cell volume blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your Prothrombin time and Packed cell volume Test reports by your pathologist.

Medical References

• MedlinePlus – Prothrombin Time Test and INR (PT/INR)
• Mayo Clinic – Prothrombin time test
• Cleveland Clinic – Prothrombin Time (PT/INR) Test