What causes high Thrombin Time and low BUN?

High Thrombin Time and low BUN can be caused by many reasons.

If your Thrombin Time is in between 14 sec and 23 sec and your BUN is in between 6 mg/dL and 20 mg/dL then you need not worry as these are the normal ranges for Thrombin Time and BUN respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease Thrombin Time levels include:

• Anticoagulation drug (warfarin) therapy
• Vitamin K abnormality
• Decreased or defective factor I (fibrinogen), II (prothrombin), V or X
• Hemophilia A and hemophilia B
• Autoantibody against a specific factor (e.g., factor VIII)

Normal range of Thrombin Time : 14 - 23 sec

Ideal values of Thrombin Time depending on age :

Age	Ideal Thrombin Time value
<5 years	1.01
5-10 years	1.021
10-15 years	1.032
15-20 years	1.043
20-25 years	1.054
25-30 years	1.065
30-35 years	1.076
35-40 years	1.087
40-45 years	1.098
45-50 years	1.109
50-55 years	1.121
55-60 years	1.133
60-70 years	1.145
70-80 years	1.157
80-90 years	1.169
90-100 years	1.181
>100 years	1.193

*Ideal values are calculated based on our database of patient records

Normal range of BUN : 6 - 20 mg/dL

Ideal values of BUN depending on age :

Age	Ideal BUN value
<5 years	6.062
5-10 years	6.125
10-15 years	6.189
15-20 years	6.253
20-25 years	6.318
25-30 years	6.384
30-35 years	6.45
35-40 years	6.517
40-45 years	6.585
45-50 years	6.654
50-55 years	6.723
55-60 years	6.793
60-70 years	6.864
70-80 years	6.935
80-90 years	7.007
90-100 years	7.08
>100 years	7.154

High Thrombin Time and low BUN can be caused by a lot of reasons. If you take Thrombin Time and BUN blood tests and the results are higher than 23 sec for Thrombin Time and lower than 6 mg/dL for BUN, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the Thrombin Time and BUN Tests Are Done :

If your doctor wants Thrombin Time and BUN tests on you, you may need to go through these tests. During the Thrombin Time and BUN blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your Thrombin Time and BUN Test reports by your pathologist.

Medical References

• PubMed – Thrombin clotting time
• NIH – Coagulation Tests
• PubMed – The thrombin clotting time. Evaluation of Thromboquik