What causes high Thrombin Time and low Calcium?

High Thrombin Time and low Calcium can be caused by many reasons.

If your Thrombin Time is in between 14 sec and 23 sec and your Calcium is in between 8.5 mg/dL and 10.1 mg/dL then you need not worry as these are the normal ranges for Thrombin Time and Calcium respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease Thrombin Time levels include:

• Anticoagulation drug (warfarin) therapy
• Vitamin K abnormality
• Decreased or defective factor I (fibrinogen), II (prothrombin), V or X
• Hemophilia A and hemophilia B
• Autoantibody against a specific factor (e.g., factor VIII)

Normal range of Thrombin Time : 14 - 23 sec

Ideal values of Thrombin Time depending on age :

Age	Ideal Thrombin Time value
<5 years	1.01
5-10 years	1.02
10-15 years	1.031
15-20 years	1.042
20-25 years	1.053
25-30 years	1.064
30-35 years	1.075
35-40 years	1.086
40-45 years	1.097
45-50 years	1.108
50-55 years	1.119
55-60 years	1.131
60-70 years	1.143
70-80 years	1.155
80-90 years	1.167
90-100 years	1.179
>100 years	1.191

*Ideal values are calculated based on our database of patient records

Normal range of Calcium : 8.5 - 10.1 mg/dL

Ideal values of Calcium depending on age :

Age	Ideal Calcium value
<5 years	8.588
5-10 years	8.677
10-15 years	8.767
15-20 years	8.857
20-25 years	8.948
25-30 years	9.04
30-35 years	9.133
35-40 years	9.227
40-45 years	9.322
45-50 years	9.418
50-55 years	9.515
55-60 years	9.613
60-70 years	9.712
70-80 years	9.812
80-90 years	9.913
90-100 years	10.015
>100 years	10.014

High Thrombin Time and low Calcium can be caused by a lot of reasons. If you take Thrombin Time and Calcium blood tests and the results are higher than 23 sec for Thrombin Time and lower than 8.5 mg/dL for Calcium, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the Thrombin Time and Calcium Tests Are Done :

If your doctor wants Thrombin Time and Calcium tests on you, you may need to go through these tests. During the Thrombin Time and Calcium blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your Thrombin Time and Calcium Test reports by your pathologist.

Medical References

• PubMed – Thrombin clotting time
• NIH – Coagulation Tests
• PubMed – The thrombin clotting time. Evaluation of Thromboquik