What causes high TIBC and low Alkaline phosphatase?

High TIBC and low Alkaline phosphatase can be caused by many reasons.

If your TIBC is in between 250 mcg/dL and 450 mcg/dL and your Alkaline phosphatase is in between 30 U/L and 120 U/L then you need not worry as these are the normal ranges for TIBC and Alkaline phosphatase respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease TIBC levels include:

• Iron deficiency
• Iron poisoning
• Inflammation
• Chronic liver disease
• Hemochromatosis

TIBC treatment - Click to read 10 GOLDEN ARTICLES on Anemia

Normal range of TIBC : 250 - 450 mcg/dL

Ideal values of TIBC depending on age :

Age	Ideal TIBC value
<5 years	254.32
5-10 years	258.715
10-15 years	263.186
15-20 years	267.734
20-25 years	272.36
25-30 years	277.066
30-35 years	281.854
35-40 years	286.724
40-45 years	291.679
45-50 years	296.719
50-55 years	301.846
55-60 years	307.062
60-70 years	312.368
70-80 years	317.766
80-90 years	323.257
90-100 years	328.843
>100 years	334.525

*Ideal values are calculated based on our database of patient records

Normal range of Alkaline phosphatase : 30 - 120 U/L

Ideal values of Alkaline phosphatase depending on age :

Age	Ideal Alkaline phosphatase value
<5 years	30.518
5-10 years	31.045
10-15 years	31.581
15-20 years	32.127
20-25 years	32.682
25-30 years	33.247
30-35 years	33.822
35-40 years	34.406
40-45 years	35.001
45-50 years	35.606
50-55 years	36.221
55-60 years	36.847
60-70 years	37.484
70-80 years	38.132
80-90 years	38.791
90-100 years	39.461
>100 years	40.143

High TIBC and low Alkaline phosphatase can be caused by a lot of reasons. If you take TIBC and Alkaline phosphatase blood tests and the results are higher than 450 mcg/dL for TIBC and lower than 30 U/L for Alkaline phosphatase, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the TIBC and Alkaline phosphatase Tests Are Done :

If your doctor wants TIBC and Alkaline phosphatase tests on you, you may need to go through these tests. During the TIBC and Alkaline phosphatase blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your TIBC and Alkaline phosphatase Test reports by your pathologist.

Medical References

• Cleveland Clinic – TIBC (Total Iron-Binding Capacity) Test
• WebMD – What to Know About Total Iron-Binding Capacity (TIBC) Test
• MedlinePlus – Total iron binding capacity