What causes high TIBC and low Ferritin?

High TIBC and low Ferritin can be caused by many reasons.

If your TIBC is in between 250 mcg/dL and 450 mcg/dL and your Ferritin is in between 22 ng/mL and 322 ng/mL then you need not worry as these are the normal ranges for TIBC and Ferritin respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease TIBC levels include:

• Iron deficiency
• Iron poisoning
• Inflammation
• Chronic liver disease
• Hemochromatosis

TIBC treatment - Click to read 10 GOLDEN ARTICLES on Anemia

Normal range of TIBC : 250 - 450 mcg/dL

Ideal values of TIBC depending on age :

Age	Ideal TIBC value
<5 years	254.328
5-10 years	258.73
10-15 years	263.209
15-20 years	267.765
20-25 years	272.4
25-30 years	277.115
30-35 years	281.912
35-40 years	286.792
40-45 years	291.756
45-50 years	296.806
50-55 years	301.944
55-60 years	307.171
60-70 years	312.488
70-80 years	317.897
80-90 years	323.4
90-100 years	328.998
>100 years	334.693

*Ideal values are calculated based on our database of patient records

Normal range of Ferritin : 22 - 322 ng/mL

Ideal values of Ferritin depending on age :

Age	Ideal Ferritin value
<5 years	22.381
5-10 years	22.768
10-15 years	23.162
15-20 years	23.563
20-25 years	23.971
25-30 years	24.386
30-35 years	24.808
35-40 years	25.237
40-45 years	25.674
45-50 years	26.118
50-55 years	26.57
55-60 years	27.03
60-70 years	27.498
70-80 years	27.974
80-90 years	28.458
90-100 years	28.951
>100 years	29.452

High TIBC and low Ferritin can be caused by a lot of reasons. If you take TIBC and Ferritin blood tests and the results are higher than 450 mcg/dL for TIBC and lower than 22 ng/mL for Ferritin, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the TIBC and Ferritin Tests Are Done :

If your doctor wants TIBC and Ferritin tests on you, you may need to go through these tests. During the TIBC and Ferritin blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your TIBC and Ferritin Test reports by your pathologist.

Medical References

• Cleveland Clinic – TIBC (Total Iron-Binding Capacity) Test
• WebMD – What to Know About Total Iron-Binding Capacity (TIBC) Test
• MedlinePlus – Total iron binding capacity