What causes high TIBC and low Packed cell volume?

High TIBC and low Packed cell volume can be caused by many reasons.

If your TIBC is in between 250 mcg/dL and 450 mcg/dL and your Packed cell volume is in between 41 % and 49.5 % then you need not worry as these are the normal ranges for TIBC and Packed cell volume respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease TIBC levels include:

• Iron deficiency
• Iron poisoning
• Inflammation
• Chronic liver disease
• Hemochromatosis

TIBC treatment - Click to read 10 GOLDEN ARTICLES on Anemia

Normal range of TIBC : 250 - 450 mcg/dL

Ideal values of TIBC depending on age :

Age	Ideal TIBC value
<5 years	254.405
5-10 years	258.888
10-15 years	263.45
15-20 years	268.092
20-25 years	272.816
25-30 years	277.623
30-35 years	282.515
35-40 years	287.493
40-45 years	292.559
45-50 years	297.714
50-55 years	302.96
55-60 years	308.298
60-70 years	313.73
70-80 years	319.258
80-90 years	324.883
90-100 years	330.607
>100 years	336.432

*Ideal values are calculated based on our database of patient records

Normal range of Packed cell volume : 41 - 49.5 %

Ideal values of Packed cell volume depending on age :

Age	Ideal Packed cell volume value
<5 years	41.722
5-10 years	42.457
10-15 years	43.205
15-20 years	43.966
20-25 years	44.741
25-30 years	45.529
30-35 years	46.331
35-40 years	47.147
40-45 years	47.978
45-50 years	48.823
50-55 years	48.808
55-60 years	48.793
60-70 years	48.778
70-80 years	48.762
80-90 years	48.747
90-100 years	48.732
>100 years	48.717

High TIBC and low Packed cell volume can be caused by a lot of reasons. If you take TIBC and Packed cell volume blood tests and the results are higher than 450 mcg/dL for TIBC and lower than 41 % for Packed cell volume, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the TIBC and Packed cell volume Tests Are Done :

If your doctor wants TIBC and Packed cell volume tests on you, you may need to go through these tests. During the TIBC and Packed cell volume blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your TIBC and Packed cell volume Test reports by your pathologist.

Medical References

• Cleveland Clinic – TIBC (Total Iron-Binding Capacity) Test
• WebMD – What to Know About Total Iron-Binding Capacity (TIBC) Test
• MedlinePlus – Total iron binding capacity