What causes high TIBC and low Prothrombin time?

High TIBC and low Prothrombin time can be caused by many reasons.

If your TIBC is in between 250 mcg/dL and 450 mcg/dL and your Prothrombin time is in between 12 seconds and 16 seconds then you need not worry as these are the normal ranges for TIBC and Prothrombin time respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease TIBC levels include:

• Iron deficiency
• Iron poisoning
• Inflammation
• Chronic liver disease
• Hemochromatosis

TIBC treatment - Click to read 10 GOLDEN ARTICLES on Anemia

Normal range of TIBC : 250 - 450 mcg/dL

Ideal values of TIBC depending on age :

Age	Ideal TIBC value
<5 years	254.42
5-10 years	258.918
10-15 years	263.496
15-20 years	268.155
20-25 years	272.896
25-30 years	277.721
30-35 years	282.631
35-40 years	287.628
40-45 years	292.713
45-50 years	297.888
50-55 years	303.155
55-60 years	308.515
60-70 years	313.97
70-80 years	319.521
80-90 years	325.17
90-100 years	330.919
>100 years	336.77

*Ideal values are calculated based on our database of patient records

Normal range of Prothrombin time : 12 - 16 seconds

Ideal values of Prothrombin time depending on age :

Age	Ideal Prothrombin time value
<5 years	12.212
5-10 years	12.428
10-15 years	12.648
15-20 years	12.872
20-25 years	13.1
25-30 years	13.332
30-35 years	13.568
35-40 years	13.808
40-45 years	14.052
45-50 years	14.3
50-55 years	14.553
55-60 years	14.81
60-70 years	15.072
70-80 years	15.338
80-90 years	15.609
90-100 years	15.885
>100 years	15.88

High TIBC and low Prothrombin time can be caused by a lot of reasons. If you take TIBC and Prothrombin time blood tests and the results are higher than 450 mcg/dL for TIBC and lower than 12 seconds for Prothrombin time, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the TIBC and Prothrombin time Tests Are Done :

If your doctor wants TIBC and Prothrombin time tests on you, you may need to go through these tests. During the TIBC and Prothrombin time blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your TIBC and Prothrombin time Test reports by your pathologist.

Medical References

• Cleveland Clinic – TIBC (Total Iron-Binding Capacity) Test
• WebMD – What to Know About Total Iron-Binding Capacity (TIBC) Test
• MedlinePlus – Total iron binding capacity