What causes high TIBC and low Total serum iron?

High TIBC and low Total serum iron can be caused by many reasons.

If your TIBC is in between 250 mcg/dL and 450 mcg/dL and your Total serum iron is in between 40 mcg/dL and 190 mcg/dL then you need not worry as these are the normal ranges for TIBC and Total serum iron respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease TIBC levels include:

• Iron deficiency
• Iron poisoning
• Inflammation
• Chronic liver disease
• Hemochromatosis

TIBC treatment - Click to read 10 GOLDEN ARTICLES on Anemia

Normal range of TIBC : 250 - 450 mcg/dL

Ideal values of TIBC depending on age :

Age	Ideal TIBC value
<5 years	254.43
5-10 years	258.938
10-15 years	263.526
15-20 years	268.196
20-25 years	272.948
25-30 years	277.785
30-35 years	282.707
35-40 years	287.717
40-45 years	292.815
45-50 years	298.004
50-55 years	303.285
55-60 years	308.659
60-70 years	314.128
70-80 years	319.694
80-90 years	325.359
90-100 years	331.124
>100 years	336.992

*Ideal values are calculated based on our database of patient records

Normal range of Total serum iron : 40 - 190 mcg/dL

Ideal values of Total serum iron depending on age :

Age	Ideal Total serum iron value
<5 years	40.709
5-10 years	41.43
10-15 years	42.164
15-20 years	42.911
20-25 years	43.671
25-30 years	44.445
30-35 years	45.233
35-40 years	46.035
40-45 years	46.851
45-50 years	47.681
50-55 years	48.526
55-60 years	49.386
60-70 years	50.261
70-80 years	51.152
80-90 years	52.058
90-100 years	52.98
>100 years	53.919

High TIBC and low Total serum iron can be caused by a lot of reasons. If you take TIBC and Total serum iron blood tests and the results are higher than 450 mcg/dL for TIBC and lower than 40 mcg/dL for Total serum iron, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the TIBC and Total serum iron Tests Are Done :

If your doctor wants TIBC and Total serum iron tests on you, you may need to go through these tests. During the TIBC and Total serum iron blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your TIBC and Total serum iron Test reports by your pathologist.

Medical References

• Cleveland Clinic – TIBC (Total Iron-Binding Capacity) Test
• WebMD – What to Know About Total Iron-Binding Capacity (TIBC) Test
• MedlinePlus – Total iron binding capacity