What causes high Transferrin saturation and low Cystatin c?

High Transferrin saturation and low Cystatin c can be caused by many reasons.

If your Transferrin saturation is in between 13 % and 45 % and your Cystatin c is in between 0.62 mg/L and 1.03 mg/L then you need not worry as these are the normal ranges for Transferrin saturation and Cystatin c respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease Transferrin saturation levels include:

• Anemia
• Your body doesnt have enough healthy red blood cells
• Chronic Illness
• Iron poisoning
• Gastrointestinal blood loss

Transferrin saturation treatment - Click to read 10 GOLDEN ARTICLES on Anemia

Normal range of Transferrin saturation : 13 - 45 %

Ideal values of Transferrin saturation depending on age :

Age	Ideal Transferrin saturation value
<5 years	13.22867
5-10 years	13.46136
10-15 years	13.69815
15-20 years	13.9391
20-25 years	14.18429
25-30 years	14.43379
30-35 years	14.68768
35-40 years	14.94604
40-45 years	15.20894
45-50 years	15.47647
50-55 years	15.7487
55-60 years	16.02572
60-70 years	16.30761
70-80 years	16.59446
80-90 years	16.88636
90-100 years	17.18339
>100 years	17.48565

*Ideal values are calculated based on our database of patient records

Normal range of Cystatin c : 0.62 - 1.03 mg/L

Ideal values of Cystatin c depending on age :

Age	Ideal Cystatin c value
<5 years	0.631
5-10 years	0.642
10-15 years	0.653
15-20 years	0.664
20-25 years	0.676
25-30 years	0.688
30-35 years	0.7
35-40 years	0.712
40-45 years	0.725
45-50 years	0.738
50-55 years	0.751
55-60 years	0.764
60-70 years	0.777
70-80 years	0.791
80-90 years	0.805
90-100 years	0.819
>100 years	0.833

High Transferrin saturation and low Cystatin c can be caused by a lot of reasons. If you take Transferrin saturation and Cystatin c blood tests and the results are higher than 45 % for Transferrin saturation and lower than 0.62 mg/L for Cystatin c, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the Transferrin saturation and Cystatin c Tests Are Done :

If your doctor wants Transferrin saturation and Cystatin c tests on you, you may need to go through these tests. During the Transferrin saturation and Cystatin c blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your Transferrin saturation and Cystatin c Test reports by your pathologist.

Medical References

• Cleveland Clinic – TIBC (Total Iron-Binding Capacity) Test
• MedlinePlus – Total iron binding capacity
• Mayo Clinic – Hemochromatosis - Diagnosis and treatment