What causes high Transferrin saturation and low Ferritin?

High Transferrin saturation and low Ferritin can be caused by many reasons.

If your Transferrin saturation is in between 13 % and 45 % and your Ferritin is in between 22 ng/mL and 322 ng/mL then you need not worry as these are the normal ranges for Transferrin saturation and Ferritin respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease Transferrin saturation levels include:

• Anemia
• Your body doesnt have enough healthy red blood cells
• Chronic Illness
• Iron poisoning
• Gastrointestinal blood loss

Transferrin saturation treatment - Click to read 10 GOLDEN ARTICLES on Anemia

Normal range of Transferrin saturation : 13 - 45 %

Ideal values of Transferrin saturation depending on age :

Age	Ideal Transferrin saturation value
<5 years	13.22503
5-10 years	13.45396
10-15 years	13.68685
15-20 years	13.92377
20-25 years	14.16479
25-30 years	14.40998
30-35 years	14.65942
35-40 years	14.91317
40-45 years	15.17132
45-50 years	15.43394
50-55 years	15.7011
55-60 years	15.97289
60-70 years	16.24938
70-80 years	16.53066
80-90 years	16.81681
90-100 years	17.10791
>100 years	17.40405

*Ideal values are calculated based on our database of patient records

Normal range of Ferritin : 22 - 322 ng/mL

Ideal values of Ferritin depending on age :

Age	Ideal Ferritin value
<5 years	22.381
5-10 years	22.768
10-15 years	23.162
15-20 years	23.563
20-25 years	23.971
25-30 years	24.386
30-35 years	24.808
35-40 years	25.237
40-45 years	25.674
45-50 years	26.118
50-55 years	26.57
55-60 years	27.03
60-70 years	27.498
70-80 years	27.974
80-90 years	28.458
90-100 years	28.951
>100 years	29.452

High Transferrin saturation and low Ferritin can be caused by a lot of reasons. If you take Transferrin saturation and Ferritin blood tests and the results are higher than 45 % for Transferrin saturation and lower than 22 ng/mL for Ferritin, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the Transferrin saturation and Ferritin Tests Are Done :

If your doctor wants Transferrin saturation and Ferritin tests on you, you may need to go through these tests. During the Transferrin saturation and Ferritin blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your Transferrin saturation and Ferritin Test reports by your pathologist.

Medical References

• Cleveland Clinic – TIBC (Total Iron-Binding Capacity) Test
• MedlinePlus – Total iron binding capacity
• Mayo Clinic – Hemochromatosis - Diagnosis and treatment