What causes high Transferrin saturation and low MCHC?

High Transferrin saturation and low MCHC can be caused by many reasons.

If your Transferrin saturation is in between 13 % and 45 % and your MCHC is in between 31.5 g/dL and 34.5 g/dL then you need not worry as these are the normal ranges for Transferrin saturation and MCHC respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease Transferrin saturation levels include:

• Anemia
• Your body doesnt have enough healthy red blood cells
• Chronic Illness
• Iron poisoning
• Gastrointestinal blood loss

Transferrin saturation treatment - Click to read 10 GOLDEN ARTICLES on Anemia

Normal range of Transferrin saturation : 13 - 45 %

Ideal values of Transferrin saturation depending on age :

Age	Ideal Transferrin saturation value
<5 years	13.22191
5-10 years	13.44761
10-15 years	13.67716
15-20 years	13.91063
20-25 years	14.14808
25-30 years	14.38959
30-35 years	14.63522
35-40 years	14.88504
40-45 years	15.13913
45-50 years	15.39755
50-55 years	15.66039
55-60 years	15.92771
60-70 years	16.1996
70-80 years	16.47613
80-90 years	16.75738
90-100 years	17.04343
>100 years	17.33436

*Ideal values are calculated based on our database of patient records

Normal range of MCHC : 31.5 - 34.5 g/dL

Ideal values of MCHC depending on age :

Age	Ideal MCHC value
<5 years	32.038
5-10 years	32.585
10-15 years	33.141
15-20 years	33.707
20-25 years	34.282
25-30 years	34.272
30-35 years	34.262
35-40 years	34.252
40-45 years	34.242
45-50 years	34.233
50-55 years	34.223
55-60 years	34.213
60-70 years	34.203
70-80 years	34.193
80-90 years	34.183
90-100 years	34.174
>100 years	34.164

High Transferrin saturation and low MCHC can be caused by a lot of reasons. If you take Transferrin saturation and MCHC blood tests and the results are higher than 45 % for Transferrin saturation and lower than 31.5 g/dL for MCHC, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the Transferrin saturation and MCHC Tests Are Done :

If your doctor wants Transferrin saturation and MCHC tests on you, you may need to go through these tests. During the Transferrin saturation and MCHC blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your Transferrin saturation and MCHC Test reports by your pathologist.

Medical References

• Cleveland Clinic – TIBC (Total Iron-Binding Capacity) Test
• MedlinePlus – Total iron binding capacity
• Mayo Clinic – Hemochromatosis - Diagnosis and treatment