What causes high Transferrin saturation and low TIBC?

High Transferrin saturation and low TIBC can be caused by many reasons.

If your Transferrin saturation is in between 13 % and 45 % and your TIBC is in between 250 mcg/dL and 450 mcg/dL then you need not worry as these are the normal ranges for Transferrin saturation and TIBC respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Some examples of conditions that can increase or decrease Transferrin saturation levels include:

• Anemia
• Your body doesnt have enough healthy red blood cells
• Chronic Illness
• Iron poisoning
• Gastrointestinal blood loss

Transferrin saturation treatment - Click to read 10 GOLDEN ARTICLES on Anemia

Normal range of Transferrin saturation : 13 - 45 %

Ideal values of Transferrin saturation depending on age :

Age	Ideal Transferrin saturation value
<5 years	13.23023
5-10 years	13.46454
10-15 years	13.703
15-20 years	13.94568
20-25 years	14.19266
25-30 years	14.44401
30-35 years	14.69981
35-40 years	14.96014
40-45 years	15.22508
45-50 years	15.49472
50-55 years	15.76913
55-60 years	16.0484
60-70 years	16.33262
70-80 years	16.62187
80-90 years	16.91624
90-100 years	17.21583
>100 years	17.52072

*Ideal values are calculated based on our database of patient records

Normal range of TIBC : 250 - 450 mcg/dL

Ideal values of TIBC depending on age :

Age	Ideal TIBC value
<5 years	254.428
5-10 years	258.934
10-15 years	263.52
15-20 years	268.187
20-25 years	272.937
25-30 years	277.771
30-35 years	282.69
35-40 years	287.696
40-45 years	292.791
45-50 years	297.976
50-55 years	303.253
55-60 years	308.624
60-70 years	314.09
70-80 years	319.653
80-90 years	325.314
90-100 years	331.075
>100 years	336.938

High Transferrin saturation and low TIBC can be caused by a lot of reasons. If you take Transferrin saturation and TIBC blood tests and the results are higher than 45 % for Transferrin saturation and lower than 250 mcg/dL for TIBC, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the Transferrin saturation and TIBC Tests Are Done :

If your doctor wants Transferrin saturation and TIBC tests on you, you may need to go through these tests. During the Transferrin saturation and TIBC blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your Transferrin saturation and TIBC Test reports by your pathologist.

Medical References

• Cleveland Clinic – TIBC (Total Iron-Binding Capacity) Test
• MedlinePlus – Total iron binding capacity
• Mayo Clinic – Hemochromatosis - Diagnosis and treatment